The NuRD complex cooperates with SALL4 to orchestrate reprogramming

Cell fate decision involves rewiring of the genome, but remains poorly understood at the chromatin level. Here, we report that chromatin remodeling complex NuRD participates in closing open chromatin in the early phase of somatic reprogramming. Sall4, Jdp2, Glis1 and Esrrb can reprogram MEFs to iPSC...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Chen, Ming, Jin, Wu, Linlin, Fang, Shicai, Huang, Yi, Lin, Lihui, Liu, He, Kuang, Junqi, Zhao, Chengchen, Huang, Xingnan, Feng, Huijian, Guo, Jing, Yang, Xuejie, Guo, Liman, Zhang, Xiaofei, Chen, Jiekai, Liu, Jing, Zhu, Ping, Pei, Duanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199099/
https://www.ncbi.nlm.nih.gov/pubmed/37208322
http://dx.doi.org/10.1038/s41467-023-38543-0

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