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Effect of a high‐fat and high‐calorie food on the pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy subjects
HSK16149 is a novel, potent gamma‐aminobutyric acid (GABA) analog for the treatment of neuropathic pain. The purpose of this study was to assess the effect of a high‐fat and high‐calorie meal on the pharmacokinetics of HSK16149 in healthy Chinese subjects. An open‐label, two‐period crossover design...
Autores principales: | Wu, Qingqing, Zhu, Huijuan, Song, Rong, Zhang, Mengqi, Li, Fangqiong, Zeng, Weifang, Wang, Wei, Jia, Jingying, Yu, Chen, Liu, Yanmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199234/ https://www.ncbi.nlm.nih.gov/pubmed/37208866 http://dx.doi.org/10.1002/prp2.1102 |
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