RUNX1 colludes with NOTCH1 to reprogram chromatin in T cell acute lymphoblastic leukemia

Runt-related transcription factor 1 (RUNX1) is oncogenic in diverse types of leukemia and epithelial cancers where its expression is associated with poor prognosis. Current models suggest that RUNX1 cooperates with other oncogenic factors (e.g., NOTCH1, TAL1) to drive the expression of proto-oncogen...

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Detalles Bibliográficos
Autores principales: Islam, Rashedul, Jenkins, Catherine E., Cao, Qi, Wong, Jasper, Bilenky, Misha, Carles, Annaïck, Moksa, Michelle, Weng, Andrew P., Hirst, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199266/
https://www.ncbi.nlm.nih.gov/pubmed/37213235
http://dx.doi.org/10.1016/j.isci.2023.106795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199266/
https://www.ncbi.nlm.nih.gov/pubmed/37213235
http://dx.doi.org/10.1016/j.isci.2023.106795

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