Dysbiosis of gut microbiota inhibits NMNAT2 to promote neurobehavioral deficits and oxidative stress response in the 6-OHDA-lesioned rat model of Parkinson’s disease

BACKGROUND: New data are accumulating on gut microbial dysbiosis in Parkinson’s disease (PD), while the specific mechanism remains uncharacterized. This study aims to investigate the potential role and pathophysiological mechanism of dysbiosis of gut microbiota in 6-hydroxydopamine (6-OHDA)-induced...

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Detalles Bibliográficos
Autores principales: Yu, Jianjun, Meng, Jianhong, Qin, Zhengwei, Yu, Yuan, Liang, Yingxin, Wang, Yanjun, Min, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199500/
https://www.ncbi.nlm.nih.gov/pubmed/37208728
http://dx.doi.org/10.1186/s12974-023-02782-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199500/
https://www.ncbi.nlm.nih.gov/pubmed/37208728
http://dx.doi.org/10.1186/s12974-023-02782-1

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