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EZH2 mediated metabolic rewiring promotes tumor growth independently of histone methyltransferase activity in ovarian cancer

BACKGROUND: Enhancer of zeste homolog 2 (EZH2), the key catalytic subunit of polycomb repressive complex 2 (PRC2), is overexpressed and plays an oncogenic role in various cancers through catalysis-dependent or catalysis-independent pathways. However, the related mechanisms contributing to ovarian ca...

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Detalles Bibliográficos
Autores principales:	Chen, Jianfeng, Hong, Jing Han, Huang, Yulin, Liu, Shini, Yin, Jiaxin, Deng, Peng, Sun, Yichen, Yu, Zhaoliang, Zeng, Xian, Xiao, Rong, Chan, Jason Yongsheng, Guan, Peiyong, Wang, Yali, Wang, Peili, Liu, Lizhen, Wen, Shijun, Yu, Qiang, Ong, Choon Kiat, Teh, Bin-Tean, Xiong, Ying, Tan, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199584/ https://www.ncbi.nlm.nih.gov/pubmed/37210576 http://dx.doi.org/10.1186/s12943-023-01786-y

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