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HDAC3 deficiency protects against acute lung injury by maintaining epithelial barrier integrity through preserving mitochondrial quality control
Sepsis is one common cause of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), which is closely associated with high mortality in intensive care units (ICU). Histone deacetylase 3 (HDAC3) serves as an important epigenetic modifying enzyme which could affect chromatin structure...
Autores principales: | Li, Ning, Liu, Bohao, Xiong, Rui, Li, Guorui, Wang, Bo, Geng, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199751/ https://www.ncbi.nlm.nih.gov/pubmed/37244125 http://dx.doi.org/10.1016/j.redox.2023.102746 |
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