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NCX2 Regulates Intracellular Calcium Homeostasis and Translocation of HIF-1α into the Nucleus to Inhibit Glioma Invasion
Glioma is the most common tumor of the central nervous system, and its poor prognosis can be linked to hypoxia and gene inactivation. Na(+)/Ca(2+) exchanger 2 (NCX2) is expressed only in the normal brain and not in other tissues or glioma. We constructed a hypoxic microenvironment to more accurately...
Autores principales: | Liu, Hongyuan, Yu, Ju, Yang, Liling, He, Pengcheng, Li, Zongping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199856/ https://www.ncbi.nlm.nih.gov/pubmed/36334237 http://dx.doi.org/10.1007/s10528-022-10274-9 |
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