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Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD(+)/SIRT3 pathway

Emerging evidence suggests that mitochondria play a central role in mental health disorders including schizophrenia. Here we investigated whether nicotinamide (NAM) normalized cognitive impairment via a mechanism involving the mitochondrial Sirtuin 3 (SIRT3) pathway. The 24 h maternal separation (MS...

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Detalles Bibliográficos
Autores principales: Hao, Keke, Chen, Fashuai, Zhao, Linyao, Xu, Shilin, Xiong, Ying, Xu, Rui, Xie, Xinhui, Huang, Huan, Shu, Chang, Liu, Zhongchun, Wang, Huiling, Wang, Gaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199898/
https://www.ncbi.nlm.nih.gov/pubmed/37210391
http://dx.doi.org/10.1038/s41537-023-00357-w