Metabolic function-based normalization improves transcriptome data-driven reduction of genome-scale metabolic models

Genome-scale metabolic models (GEMs) are extensively used to simulate cell metabolism and predict cell phenotypes. GEMs can also be tailored to generate context-specific GEMs, using omics data integration approaches. To date, many integration approaches have been developed, however, each with specif...

Descripción completa

Detalles Bibliográficos
Autores principales: Jalili, Mahdi, Scharm, Martin, Wolkenhauer, Olaf, Salehzadeh-Yazdi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199931/
https://www.ncbi.nlm.nih.gov/pubmed/37210409
http://dx.doi.org/10.1038/s41540-023-00281-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199931/
https://www.ncbi.nlm.nih.gov/pubmed/37210409
http://dx.doi.org/10.1038/s41540-023-00281-w

Ejemplares similares