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Metabolic function-based normalization improves transcriptome data-driven reduction of genome-scale metabolic models
Genome-scale metabolic models (GEMs) are extensively used to simulate cell metabolism and predict cell phenotypes. GEMs can also be tailored to generate context-specific GEMs, using omics data integration approaches. To date, many integration approaches have been developed, however, each with specif...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199931/ https://www.ncbi.nlm.nih.gov/pubmed/37210409 http://dx.doi.org/10.1038/s41540-023-00281-w |