Cargando…
Phase II trial of fulvestrant plus enzalutamide in ER+/HER2− advanced breast cancer
This clinical trial combined fulvestrant with the anti-androgen enzalutamide in women with metastatic ER+/HER2− breast cancer (BC). Eligible patients were women with ECOG 0–2, ER+/HER2− measurable or evaluable metastatic BC. Prior fulvestrant was allowed. Fulvestrant was administered at 500 mg IM on...
Autores principales: | Elias, Anthony D., Spoelstra, Nicole S., Staley, Alyse W., Sams, Sharon, Crump, Lyndsey S., Vidal, Gregory A., Borges, Virginia F., Kabos, Peter, Diamond, Jennifer R., Shagisultanova, Elena, Afghahi, Anosheh, Mayordomo, Jose, McSpadden, Tessa, Crawford, Gloria, D’Alessandro, Angelo, Zolman, Kathryn L., van Bokhoven, Adrie, Zhuang, Yonghua, Gallagher, Rosa I., Wulfkuhle, Julia D., Petricoin III, Emanuel F., Gao, Dexiang, Richer, Jennifer K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199936/ https://www.ncbi.nlm.nih.gov/pubmed/37210417 http://dx.doi.org/10.1038/s41523-023-00544-z |
Ejemplares similares
-
OR30-5 Androgen-Regulated Secreted Factors Promote Tumorigenesis and Immune Suppression in Breast Cancer
por: Richer, Jennifer, et al.
Publicado: (2022) -
A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer
por: Diamond, Jennifer R., et al.
Publicado: (2018) -
Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis
por: Dahut, Madeline, et al.
Publicado: (2023) -
Triple Targeting of Breast Tumors Driven by Hormonal Receptors and HER2
por: Shagisultanova, Elena, et al.
Publicado: (2022) -
Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide
por: Cochrane, Dawn R, et al.
Publicado: (2014)