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Effects of Different Doses of Esketamine on Pain Sensitivity of Patients Undergoing Thyroidectomy: A Randomized Controlled Trial

INTRODUCTION: Several factors may lead to increased postoperative pain sensitivity, of which remifentanil-induced hyperalgesia (RIH) is one of the main factors. High-dose remifentanil exposure during anesthesia may induce RIH. Esketamine may prevent RIH by antagonizing N-methyl-d-aspartate (NMDA) re...

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Detalles Bibliográficos
Autores principales:	Ren, Yan-ling, Yuan, Jing-jing, Xing, Fei, Zhu, Li-ning, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199971/ https://www.ncbi.nlm.nih.gov/pubmed/36933139 http://dx.doi.org/10.1007/s40122-023-00488-z

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