Post-operative Tumor Lysis Syndrome in High-Grade Uterine Sarcoma

Tumor lysis syndrome (TLS) is a well-known oncologic emergency. It is a constellation of metabolic derangements usually observed in hematological malignancies due to rapid cell lysis, typically due to chemotherapy or radiotherapy initiation. Spontaneous TLS is an unusual complication in solid malign...

Descripción completa

Detalles Bibliográficos
Autores principales: Qasim, Hana, Mahadevia, Himil J, Ponvilawan, Ben, Hamdan, Hana, Shrestha, Anuj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200365/
https://www.ncbi.nlm.nih.gov/pubmed/37220456
http://dx.doi.org/10.7759/cureus.37956
_version_ 1785045115954266112
author Qasim, Hana
Mahadevia, Himil J
Ponvilawan, Ben
Hamdan, Hana
Shrestha, Anuj
author_facet Qasim, Hana
Mahadevia, Himil J
Ponvilawan, Ben
Hamdan, Hana
Shrestha, Anuj
author_sort Qasim, Hana
collection PubMed
description Tumor lysis syndrome (TLS) is a well-known oncologic emergency. It is a constellation of metabolic derangements usually observed in hematological malignancies due to rapid cell lysis, typically due to chemotherapy or radiotherapy initiation. Spontaneous TLS is an unusual complication in solid malignancies, and only a few cases have previously been reported for spontaneous TLS in gynecological malignancies. We report a case of TLS in a 50-year-old female patient shortly after resection of high-grade uterine sarcoma. We review previous TLS cases in uterine malignancies and the associated morbidity and mortality.
format Online
Article
Text
id pubmed-10200365
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-102003652023-05-22 Post-operative Tumor Lysis Syndrome in High-Grade Uterine Sarcoma Qasim, Hana Mahadevia, Himil J Ponvilawan, Ben Hamdan, Hana Shrestha, Anuj Cureus Internal Medicine Tumor lysis syndrome (TLS) is a well-known oncologic emergency. It is a constellation of metabolic derangements usually observed in hematological malignancies due to rapid cell lysis, typically due to chemotherapy or radiotherapy initiation. Spontaneous TLS is an unusual complication in solid malignancies, and only a few cases have previously been reported for spontaneous TLS in gynecological malignancies. We report a case of TLS in a 50-year-old female patient shortly after resection of high-grade uterine sarcoma. We review previous TLS cases in uterine malignancies and the associated morbidity and mortality. Cureus 2023-04-21 /pmc/articles/PMC10200365/ /pubmed/37220456 http://dx.doi.org/10.7759/cureus.37956 Text en Copyright © 2023, Qasim et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Qasim, Hana
Mahadevia, Himil J
Ponvilawan, Ben
Hamdan, Hana
Shrestha, Anuj
Post-operative Tumor Lysis Syndrome in High-Grade Uterine Sarcoma
title Post-operative Tumor Lysis Syndrome in High-Grade Uterine Sarcoma
title_full Post-operative Tumor Lysis Syndrome in High-Grade Uterine Sarcoma
title_fullStr Post-operative Tumor Lysis Syndrome in High-Grade Uterine Sarcoma
title_full_unstemmed Post-operative Tumor Lysis Syndrome in High-Grade Uterine Sarcoma
title_short Post-operative Tumor Lysis Syndrome in High-Grade Uterine Sarcoma
title_sort post-operative tumor lysis syndrome in high-grade uterine sarcoma
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200365/
https://www.ncbi.nlm.nih.gov/pubmed/37220456
http://dx.doi.org/10.7759/cureus.37956
work_keys_str_mv AT qasimhana postoperativetumorlysissyndromeinhighgradeuterinesarcoma
AT mahadeviahimilj postoperativetumorlysissyndromeinhighgradeuterinesarcoma
AT ponvilawanben postoperativetumorlysissyndromeinhighgradeuterinesarcoma
AT hamdanhana postoperativetumorlysissyndromeinhighgradeuterinesarcoma
AT shresthaanuj postoperativetumorlysissyndromeinhighgradeuterinesarcoma

Ejemplares similares