Regulation of CD19 CAR-T cell activation based on an engineered downstream transcription factor

CAR-T cells present a highly effective therapeutic option for several malignant diseases, based on their ability to recognize the selected tumor surface marker in an MHC-independent manner. This triggers cell activation and cytokine production, resulting in the killing of the cancerous cell presenti...

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Detalles Bibliográficos
Autores principales: Lainšček, Duško, Golob-Urbanc, Anja, Mikolič, Veronika, Pantović-Žalig, Jelica, Malenšek, Špela, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200817/
https://www.ncbi.nlm.nih.gov/pubmed/37223115
http://dx.doi.org/10.1016/j.omto.2023.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200817/
https://www.ncbi.nlm.nih.gov/pubmed/37223115
http://dx.doi.org/10.1016/j.omto.2023.04.005

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