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Regulation of CD19 CAR-T cell activation based on an engineered downstream transcription factor
CAR-T cells present a highly effective therapeutic option for several malignant diseases, based on their ability to recognize the selected tumor surface marker in an MHC-independent manner. This triggers cell activation and cytokine production, resulting in the killing of the cancerous cell presenti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200817/ https://www.ncbi.nlm.nih.gov/pubmed/37223115 http://dx.doi.org/10.1016/j.omto.2023.04.005 |