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Integrin β6 deficiency protects mice from experimental colitis and colitis-associated carcinoma by altering macrophage polarization

BACKGROUND: Given the key role of integrins in maintaining intestinal homeostasis, anti-integrin biologics in inflammatory bowel disease (IBD) are being investigated in full swing. However, the unsatisfactory efficacy and safety of current anti-integrin biologics in clinical trials limit their wides...

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Detalles Bibliográficos
Autores principales:	Sun, Qi, Lu, Zhihua, Ma, Lei, Xue, Dong, Liu, Chang, Ye, Changchun, Huang, Wenbo, Dang, Yueyan, Li, Fanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10200923/ https://www.ncbi.nlm.nih.gov/pubmed/37223685 http://dx.doi.org/10.3389/fonc.2023.1190229

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