Cargando…
TyG-BMI and hypertension in Normoglycemia subjects in Japan: A cross-sectional study
BACKGROUND: Insulin Resistance (IR) are associated with Hypertension (HTN). Triglyceride glucose-body mass index (TyG-BMI) is a readily available and clinically significant indicator of IR. This study aimed to investigate whether TyG-BMI is independently associated with HTN. METHODS: A total of 15,4...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201169/ https://www.ncbi.nlm.nih.gov/pubmed/37209031 http://dx.doi.org/10.1177/14791641231173617 |
_version_ | 1785045212888825856 |
---|---|
author | Huang, Xinming He, Jiacheng Wu, Guoxin Peng, Zishu Yang, Bin Ye, Langxi |
author_facet | Huang, Xinming He, Jiacheng Wu, Guoxin Peng, Zishu Yang, Bin Ye, Langxi |
author_sort | Huang, Xinming |
collection | PubMed |
description | BACKGROUND: Insulin Resistance (IR) are associated with Hypertension (HTN). Triglyceride glucose-body mass index (TyG-BMI) is a readily available and clinically significant indicator of IR. This study aimed to investigate whether TyG-BMI is independently associated with HTN. METHODS: A total of 15,464 patients with normal blood glucose from 2004 to 2016 participated in this study. Participants were divided into four groups using the quartile method: TyG-BMI below 153.1, between 153.1 and 174.2, between 174.2 and 199.3, and over 199.3. The covariates included age, sex, BMI, WC, HDL-C, TC, TG, HbA1c, FPG, ALT, AST, GGT, SBP, DBP, smoking status, alcohol consumption, and exercise habits. RESULTS: The average age was 43.7 ± 8.9 years, and 45.4% were men. The prevalence of HTN was 6.2% (964/15464) of the population. TyG-BMI remained significantly associated with HTN after multivariate adjustment for TyG-BMI as a continuous variable (adjusted OR = 2.87, 95% CI: 1.90–4.34). Each 10-unit rise in TyG-BMI (continuous variable) was linked to a 31% increase in the prevalence of HTN (adjusted OR = 1.31, 95% CI: 1.25–1.37). In the subgroup analysis stratified by age, sex, waist circumference, and smoking status, the association between TyG-BMI and HTN were stable. CONCLUSION: In this study, TyG-BMI was highly correlated with HTN, but more experiments and different populations are needed to verify this. |
format | Online Article Text |
id | pubmed-10201169 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-102011692023-05-23 TyG-BMI and hypertension in Normoglycemia subjects in Japan: A cross-sectional study Huang, Xinming He, Jiacheng Wu, Guoxin Peng, Zishu Yang, Bin Ye, Langxi Diab Vasc Dis Res Original Article BACKGROUND: Insulin Resistance (IR) are associated with Hypertension (HTN). Triglyceride glucose-body mass index (TyG-BMI) is a readily available and clinically significant indicator of IR. This study aimed to investigate whether TyG-BMI is independently associated with HTN. METHODS: A total of 15,464 patients with normal blood glucose from 2004 to 2016 participated in this study. Participants were divided into four groups using the quartile method: TyG-BMI below 153.1, between 153.1 and 174.2, between 174.2 and 199.3, and over 199.3. The covariates included age, sex, BMI, WC, HDL-C, TC, TG, HbA1c, FPG, ALT, AST, GGT, SBP, DBP, smoking status, alcohol consumption, and exercise habits. RESULTS: The average age was 43.7 ± 8.9 years, and 45.4% were men. The prevalence of HTN was 6.2% (964/15464) of the population. TyG-BMI remained significantly associated with HTN after multivariate adjustment for TyG-BMI as a continuous variable (adjusted OR = 2.87, 95% CI: 1.90–4.34). Each 10-unit rise in TyG-BMI (continuous variable) was linked to a 31% increase in the prevalence of HTN (adjusted OR = 1.31, 95% CI: 1.25–1.37). In the subgroup analysis stratified by age, sex, waist circumference, and smoking status, the association between TyG-BMI and HTN were stable. CONCLUSION: In this study, TyG-BMI was highly correlated with HTN, but more experiments and different populations are needed to verify this. SAGE Publications 2023-05-20 /pmc/articles/PMC10201169/ /pubmed/37209031 http://dx.doi.org/10.1177/14791641231173617 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Huang, Xinming He, Jiacheng Wu, Guoxin Peng, Zishu Yang, Bin Ye, Langxi TyG-BMI and hypertension in Normoglycemia subjects in Japan: A cross-sectional study |
title | TyG-BMI and hypertension in Normoglycemia subjects in Japan: A
cross-sectional study |
title_full | TyG-BMI and hypertension in Normoglycemia subjects in Japan: A
cross-sectional study |
title_fullStr | TyG-BMI and hypertension in Normoglycemia subjects in Japan: A
cross-sectional study |
title_full_unstemmed | TyG-BMI and hypertension in Normoglycemia subjects in Japan: A
cross-sectional study |
title_short | TyG-BMI and hypertension in Normoglycemia subjects in Japan: A
cross-sectional study |
title_sort | tyg-bmi and hypertension in normoglycemia subjects in japan: a
cross-sectional study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201169/ https://www.ncbi.nlm.nih.gov/pubmed/37209031 http://dx.doi.org/10.1177/14791641231173617 |
work_keys_str_mv | AT huangxinming tygbmiandhypertensioninnormoglycemiasubjectsinjapanacrosssectionalstudy AT hejiacheng tygbmiandhypertensioninnormoglycemiasubjectsinjapanacrosssectionalstudy AT wuguoxin tygbmiandhypertensioninnormoglycemiasubjectsinjapanacrosssectionalstudy AT pengzishu tygbmiandhypertensioninnormoglycemiasubjectsinjapanacrosssectionalstudy AT yangbin tygbmiandhypertensioninnormoglycemiasubjectsinjapanacrosssectionalstudy AT yelangxi tygbmiandhypertensioninnormoglycemiasubjectsinjapanacrosssectionalstudy |