CSNK2B modulates IRF1 binding to functional DNA elements and promotes basal and agonist-induced antiviral signaling

Interferon regulatory factor 1 (IRF1) is a critical component of cell-intrinsic innate immunity that regulates both constitutive and induced antiviral defenses. Due to its short half-life, IRF1 function is generally considered to be regulated by its synthesis. However, how IRF1 activity is controlle...

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Detalles Bibliográficos
Autores principales: Matsumoto, Moe, Modliszewski, Jennifer L, Shinozaki, Kotomi, Maezawa, Reona, Perez, Vincent M, Ishikawa, Yuki, Suzuki, Ryosuke, McKnight, Kevin L, Masaki, Takahiro, Hirai-Yuki, Asuka, Kohara, Michinori, Lemon, Stanley M, Selitsky, Sara R, Yamane, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201418/
https://www.ncbi.nlm.nih.gov/pubmed/37094077
http://dx.doi.org/10.1093/nar/gkad298

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