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BESST: a novel LncRNA knockout strategy with less genome perturbance

Long noncoding RNAs (lncRNAs) are >200 nt RNA transcripts without protein-coding potential. LncRNAs can be categorized into intergenic, intronic, bidirectional, sense, and antisense lncRNAs based on the genomic localization to nearby protein-coding genes. The current CRISPR-based lncRNA knockout...

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Detalles Bibliográficos
Autores principales:	Zhang, Shikuan, Chen, Yue, Dong, Kunzhe, Zhao, Yiwan, Wang, Yanzhi, Wang, Songmao, Qu, Chen, Xu, Naihan, Xie, Weidong, Zeng, Chunyu, Lyu, Qing Rex, Zhang, Yaou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201427/ https://www.ncbi.nlm.nih.gov/pubmed/36938886 http://dx.doi.org/10.1093/nar/gkad197

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