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SirA inhibits the essential DnaA:DnaD interaction to block helicase recruitment during Bacillus subtilis sporulation

Bidirectional DNA replication from a chromosome origin requires the asymmetric loading of two helicases, one for each replisome. Our understanding of the molecular mechanisms underpinning helicase loading at bacterial chromosome origins is incomplete. Here we report both positive and negative mechan...

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Detalles Bibliográficos
Autores principales:	Winterhalter, Charles, Stevens, Daniel, Fenyk, Stepan, Pelliciari, Simone, Marchand, Elie, Soultanas, Panos, Ilangovan, Aravindan, Murray, Heath
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201431/ https://www.ncbi.nlm.nih.gov/pubmed/36416272 http://dx.doi.org/10.1093/nar/gkac1060

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