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A novel role of TRIM28 B box domain in L1 retrotransposition and ORF2p-mediated cDNA synthesis
The long interspersed element 1 (LINE-1 or L1) integration is affected by many cellular factors through various mechanisms. Some of these factors are required for L1 amplification, while others either suppress or enhance specific steps during L1 propagation. Previously, TRIM28 has been identified to...
Autores principales: | Du, Qianhui, Stow, Emily C, LaCoste, Dawn, Freeman, Benjamin, Baddoo, Melody, Shareef, Afzaal M, Miller, Kyle M, Belancio, Victoria P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201437/ https://www.ncbi.nlm.nih.gov/pubmed/37070200 http://dx.doi.org/10.1093/nar/gkad247 |
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