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Selective translational control of cellular and viral mRNAs by RPS3 mRNA binding

RPS3, a universal core component of the 40S ribosomal subunit, interacts with mRNA at the entry channel. Whether RPS3 mRNA-binding contributes to specific mRNA translation and ribosome specialization in mammalian cells is unknown. Here we mutated RPS3 mRNA-contacting residues R116, R146 and K148 and...

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Detalles Bibliográficos
Autores principales: Havkin-Solomon, Tal, Itzhaki, Elad, Joffe, Nir, Reuven, Nina, Shaul, Yosef, Dikstein, Rivka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201444/
https://www.ncbi.nlm.nih.gov/pubmed/37070189
http://dx.doi.org/10.1093/nar/gkad269

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