Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?

BACKGROUND: Creutzfeldt–Jakob disease (CJD) is a rare, fatal neurodegenerative disorder, with few months as a usual duration from onset to death. CASE PRESENTATION: In this case report, a patient of Sporadic CJD (sCJD) who presented one month after severe acute respiratory syndrome coronavirus-2 (SA...

Descripción completa

Detalles Bibliográficos
Autores principales: Alloush, Taha K., Alloush, Adel T., Abdelazeem, Yaser, Shokri, Hossam M., Abdulghani, Khaled O., Elzoghby, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201512/
https://www.ncbi.nlm.nih.gov/pubmed/37251549
http://dx.doi.org/10.1186/s41983-023-00666-y
_version_ 1785045279364349952
author Alloush, Taha K.
Alloush, Adel T.
Abdelazeem, Yaser
Shokri, Hossam M.
Abdulghani, Khaled O.
Elzoghby, Ahmed
author_facet Alloush, Taha K.
Alloush, Adel T.
Abdelazeem, Yaser
Shokri, Hossam M.
Abdulghani, Khaled O.
Elzoghby, Ahmed
author_sort Alloush, Taha K.
collection PubMed
description BACKGROUND: Creutzfeldt–Jakob disease (CJD) is a rare, fatal neurodegenerative disorder, with few months as a usual duration from onset to death. CASE PRESENTATION: In this case report, a patient of Sporadic CJD (sCJD) who presented one month after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The diagnosis of this case was established after confirming findings from clinical, neurophysiology, radiological, and laboratory features of this disease. CONCLUSION: Putting in mind all the updated data on the pathogenesis of CJD and the immune responses to SARS-CoV-2, we can suggest that COVID-19 can lead to accelerated pathogenesis and exaggerated manifestations of this fatal neurodegenerative disease.
format Online
Article
Text
id pubmed-10201512
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-102015122023-05-23 Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration? Alloush, Taha K. Alloush, Adel T. Abdelazeem, Yaser Shokri, Hossam M. Abdulghani, Khaled O. Elzoghby, Ahmed Egypt J Neurol Psychiatr Neurosurg Case Report BACKGROUND: Creutzfeldt–Jakob disease (CJD) is a rare, fatal neurodegenerative disorder, with few months as a usual duration from onset to death. CASE PRESENTATION: In this case report, a patient of Sporadic CJD (sCJD) who presented one month after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The diagnosis of this case was established after confirming findings from clinical, neurophysiology, radiological, and laboratory features of this disease. CONCLUSION: Putting in mind all the updated data on the pathogenesis of CJD and the immune responses to SARS-CoV-2, we can suggest that COVID-19 can lead to accelerated pathogenesis and exaggerated manifestations of this fatal neurodegenerative disease. Springer Berlin Heidelberg 2023-05-22 2023 /pmc/articles/PMC10201512/ /pubmed/37251549 http://dx.doi.org/10.1186/s41983-023-00666-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Case Report
Alloush, Taha K.
Alloush, Adel T.
Abdelazeem, Yaser
Shokri, Hossam M.
Abdulghani, Khaled O.
Elzoghby, Ahmed
Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?
title Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?
title_full Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?
title_fullStr Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?
title_full_unstemmed Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?
title_short Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?
title_sort creutzfeldt–jakob disease in a post-covid-19 patient: did sars-cov-2 accelerate the neurodegeneration?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201512/
https://www.ncbi.nlm.nih.gov/pubmed/37251549
http://dx.doi.org/10.1186/s41983-023-00666-y
work_keys_str_mv AT alloushtahak creutzfeldtjakobdiseaseinapostcovid19patientdidsarscov2acceleratetheneurodegeneration
AT alloushadelt creutzfeldtjakobdiseaseinapostcovid19patientdidsarscov2acceleratetheneurodegeneration
AT abdelazeemyaser creutzfeldtjakobdiseaseinapostcovid19patientdidsarscov2acceleratetheneurodegeneration
AT shokrihossamm creutzfeldtjakobdiseaseinapostcovid19patientdidsarscov2acceleratetheneurodegeneration
AT abdulghanikhaledo creutzfeldtjakobdiseaseinapostcovid19patientdidsarscov2acceleratetheneurodegeneration
AT elzoghbyahmed creutzfeldtjakobdiseaseinapostcovid19patientdidsarscov2acceleratetheneurodegeneration

Ejemplares similares