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Structural Preferences Shape the Entropic Force of Disordered Protein Ensembles

[Image: see text] Intrinsically disordered protein regions (IDRs) make up over 30% of the human proteome and exist in a dynamic conformational ensemble instead of a native, well-folded structure. Tethering IDRs to a surface (for example, the surface of a well-folded region of the same protein) can r...

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Detalles Bibliográficos
Autores principales: Yu, Feng, Sukenik, Shahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201532/
https://www.ncbi.nlm.nih.gov/pubmed/37155239
http://dx.doi.org/10.1021/acs.jpcb.3c00698

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