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Impact of a prenatal screening program on the Down syndrome phenotype: An interrupted time series analysis

INTRODUCTION: We hypothesized that children with Down syndrome who were born after the implementation of first‐trimester combined screening for trisomy 13, 18, and 21 and a second‐trimester ultrasound scan in Denmark would show a milder syndrome phenotype. We investigated the birth biometry, prevale...

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Detalles Bibliográficos
Autores principales: Steffensen, Ellen Hollands, Pedersen, Lars Henning, Lou, Stina, Vogel, Ida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201969/
https://www.ncbi.nlm.nih.gov/pubmed/37186080
http://dx.doi.org/10.1111/aogs.14573