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Aberrant distribution of T(FH) cells in aged germinal centers reduces stromal cell function

The magnitude and quality of the germinal center response after vaccination decline with age. We found that T follicular helper (T(FH)) cells are enriched in the dark zone of germinal centers in aged mice, which impairs the expansion of the follicular dendritic cell network upon immunization and red...

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Detalles Bibliográficos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2023
Materias:	Research Briefing
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202069/ https://www.ncbi.nlm.nih.gov/pubmed/37217710 http://dx.doi.org/10.1038/s41590-023-01520-2

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