EGFR Inhibition by Cetuximab Modulates Hypoxia and IFN Response Genes in Head and Neck Squamous Cell Carcinoma

Head and neck squamous cell carcinoma (HNSCC) has one of the most hypoxic and immunosuppressive tumor microenvironments (TME) among solid tumors. However, there is no proven therapeutic strategy to remodel the TME to be less hypoxic and proinflammatory. In this study, we classified tumors according...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaudhary, Ritu, Slebos, Robbert J.C., Noel, Leenil C., Song, Feifei, Poole, Maria I., Hoening, Dirk S., Hernandez-Prera, Juan C., Conejo-Garcia, Jose R., Guevara-Patino, Jose A., Wang, Xuefeng, Xie, Mengyu, Tan, Aik Choon, Chung, Christine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202124/
https://www.ncbi.nlm.nih.gov/pubmed/37377902
http://dx.doi.org/10.1158/2767-9764.CRC-22-0443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202124/
https://www.ncbi.nlm.nih.gov/pubmed/37377902
http://dx.doi.org/10.1158/2767-9764.CRC-22-0443

Ejemplares similares