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The exquisite specificity of human protein arginine methyltransferase 7 (PRMT7) toward Arg-X-Arg sites

Mammalian protein arginine methyltransferase 7 (PRMT7) has been shown to target substrates with motifs containing two arginine residues separated by one other residue (RXR motifs). In particular, the repression domain of human histone H2B (29-RKRSR-33) has been a key substrate in determining PRMT7 a...

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Detalles Bibliográficos
Autores principales:	Bondoc, Timothy J., Lowe, Troy L., Clarke, Steven G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202292/ https://www.ncbi.nlm.nih.gov/pubmed/37216364 http://dx.doi.org/10.1371/journal.pone.0285812

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