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Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity

BACKGROUND: Nail psoriasis is a challenging chronic condition affecting patients functionally and psychologically. Nail involvement is observed in 15–80% of psoriatic patients with occasional presence of isolated nail psoriasis. OBJECTIVES: To evaluate dermoscopic features of nail psoriasis and corr...

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Autores principales: Mashal, Zeinab R., Elgamal, Emad Eldin A., Zaky, Mohamed S., Elsaie, Mohamed L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202600/
https://www.ncbi.nlm.nih.gov/pubmed/37223320
http://dx.doi.org/10.1155/2023/4653177
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author Mashal, Zeinab R.
Elgamal, Emad Eldin A.
Zaky, Mohamed S.
Elsaie, Mohamed L.
author_facet Mashal, Zeinab R.
Elgamal, Emad Eldin A.
Zaky, Mohamed S.
Elsaie, Mohamed L.
author_sort Mashal, Zeinab R.
collection PubMed
description BACKGROUND: Nail psoriasis is a challenging chronic condition affecting patients functionally and psychologically. Nail involvement is observed in 15–80% of psoriatic patients with occasional presence of isolated nail psoriasis. OBJECTIVES: To evaluate dermoscopic features of nail psoriasis and correlate them clinically. METHODS: The study included fifty subjects with nail psoriasis. Psoriasis skin and nail severity was evaluated using psoriasis area severity index (PASI) and nail psoriasis severity index (NAPSI). Dermoscopy of the nails (onychoscopy) was performed, and features were recorded and analyzed. RESULTS: The most common clinical and dermoscopic findings were pitting (86%) and onycholysis (82%). Among all dermoscopic features of nail psoriasis, only longitudinal striations and subungual hyperkeratosis were significantly higher in patients with moderate to severe psoriasis than in patients with mild psoriasis (P=0.028; P=0.042, respectively). PASI scores correlated positively but none significantly with NAPSI scores (r = 0.132, P=0.360), and similarly, no significant correlation was observed between the duration of psoriasis and the dermoscopic NAPSI (r = 0.022, P=0.879). CONCLUSION: Dermoscopy can serve as a useful tool for early diagnosis of psoriatic nail changes not always visible to the naked eye and is a non-invasive easy-to-use confirmatory tool for nail changes in psoriatic disease or in isolated nail involvement.
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spelling pubmed-102026002023-05-23 Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity Mashal, Zeinab R. Elgamal, Emad Eldin A. Zaky, Mohamed S. Elsaie, Mohamed L. Dermatol Res Pract Research Article BACKGROUND: Nail psoriasis is a challenging chronic condition affecting patients functionally and psychologically. Nail involvement is observed in 15–80% of psoriatic patients with occasional presence of isolated nail psoriasis. OBJECTIVES: To evaluate dermoscopic features of nail psoriasis and correlate them clinically. METHODS: The study included fifty subjects with nail psoriasis. Psoriasis skin and nail severity was evaluated using psoriasis area severity index (PASI) and nail psoriasis severity index (NAPSI). Dermoscopy of the nails (onychoscopy) was performed, and features were recorded and analyzed. RESULTS: The most common clinical and dermoscopic findings were pitting (86%) and onycholysis (82%). Among all dermoscopic features of nail psoriasis, only longitudinal striations and subungual hyperkeratosis were significantly higher in patients with moderate to severe psoriasis than in patients with mild psoriasis (P=0.028; P=0.042, respectively). PASI scores correlated positively but none significantly with NAPSI scores (r = 0.132, P=0.360), and similarly, no significant correlation was observed between the duration of psoriasis and the dermoscopic NAPSI (r = 0.022, P=0.879). CONCLUSION: Dermoscopy can serve as a useful tool for early diagnosis of psoriatic nail changes not always visible to the naked eye and is a non-invasive easy-to-use confirmatory tool for nail changes in psoriatic disease or in isolated nail involvement. Hindawi 2023-05-15 /pmc/articles/PMC10202600/ /pubmed/37223320 http://dx.doi.org/10.1155/2023/4653177 Text en Copyright © 2023 Zeinab R. Mashal et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mashal, Zeinab R.
Elgamal, Emad Eldin A.
Zaky, Mohamed S.
Elsaie, Mohamed L.
Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity
title Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity
title_full Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity
title_fullStr Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity
title_full_unstemmed Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity
title_short Dermoscopic Features of Psoriatic Nails and Their Correlation to Disease Severity
title_sort dermoscopic features of psoriatic nails and their correlation to disease severity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202600/
https://www.ncbi.nlm.nih.gov/pubmed/37223320
http://dx.doi.org/10.1155/2023/4653177
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