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STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development

AIMS: Retinoic acid (RA) signalling is essential for heart development, and dysregulation of the RA signalling can cause several types of cardiac outflow tract (OFT) defects, the most frequent congenital heart disease (CHD) in humans. Matthew-Wood syndrome is caused by inactivating mutations of a tr...

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Detalles Bibliográficos
Autores principales: Zhou, Chikai, Häneke, Timm, Rohner, Eduarde, Sohlmér, Jesper, Kameneva, Polina, Artemov, Artem, Adameyko, Igor, Sahara, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202647/
https://www.ncbi.nlm.nih.gov/pubmed/36635482
http://dx.doi.org/10.1093/cvr/cvad010