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Neuro-mesodermal assembloids recapitulate aspects of peripheral nervous system development in vitro

Here we describe a novel neuro-mesodermal assembloid model that recapitulates aspects of peripheral nervous system (PNS) development such as neural crest cell (NCC) induction, migration, and sensory as well as sympathetic ganglion formation. The ganglia send projections to the mesodermal as well as...

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Detalles Bibliográficos
Autores principales: Rockel, Anna F., Wagner, Nicole, Spenger, Peter, Ergün, Süleyman, Wörsdörfer, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202657/
https://www.ncbi.nlm.nih.gov/pubmed/37084722
http://dx.doi.org/10.1016/j.stemcr.2023.03.012