Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner

The Matsumoto Eosinophilia Shinshu (MES) is a rat model for hereditary blood eosinophilia. The incidence of eosinophilia is 100% in both female and male MES. The primary cause of the eosinophilia in MES is a loss-of-function mutation in the gene encoding the cytochrome b-245, alpha polypeptide (Cyba...

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Autores principales: Mori, Masayuki, Dai, Jian, Miyahara, Hiroki, Li, Ying, Kang, Xiaojing, Yoshimi, Kazuto, Mashimo, Tomoji, Higuchi, Keiichi, Matsumoto, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202711/
https://www.ncbi.nlm.nih.gov/pubmed/36450519
http://dx.doi.org/10.1538/expanim.22-0122

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