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Follow-up of infants with congenital syphilis during the penicillin shortage period()

OBJECTIVE: To analyze the follow-up, in specialized outpatient clinics, of infants reported with congenital syphilis during the penicillin shortage. METHOD: A cross-sectional study was carried out in ten public maternity hospitals affiliated with the Brazilian Unified Health System in the city of Fo...

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Autores principales: Rocha, Ana Fátima Braga, Araújo, Maria Alix Leite, de Oliveira, Ana Karinne Dantas, de Oliveira, Lucas Fernandes, Pimentel, Lea Dias Gomes Vasconcelos, Melo, Adriana Lopes Lima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202725/
https://www.ncbi.nlm.nih.gov/pubmed/36584977
http://dx.doi.org/10.1016/j.jped.2022.11.011
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author Rocha, Ana Fátima Braga
Araújo, Maria Alix Leite
de Oliveira, Ana Karinne Dantas
de Oliveira, Lucas Fernandes
Pimentel, Lea Dias Gomes Vasconcelos
Melo, Adriana Lopes Lima
author_facet Rocha, Ana Fátima Braga
Araújo, Maria Alix Leite
de Oliveira, Ana Karinne Dantas
de Oliveira, Lucas Fernandes
Pimentel, Lea Dias Gomes Vasconcelos
Melo, Adriana Lopes Lima
author_sort Rocha, Ana Fátima Braga
collection PubMed
description OBJECTIVE: To analyze the follow-up, in specialized outpatient clinics, of infants reported with congenital syphilis during the penicillin shortage. METHOD: A cross-sectional study was carried out in ten public maternity hospitals affiliated with the Brazilian Unified Health System in the city of Fortaleza, state of Ceará. Clinical records of infants reported with congenital syphilis who were born alive in 2015 were used to describe correlates of attendance at recommended clinical follow-up appointments. RESULTS: A total of 469 infants reported with CS from January 1/2015 to December 31/2015 were included in the analysis. The results show that most infants did not attend the follow-up visits (368/469, 78.5%) and the main associated factors are that the follow-up clinic is located in a different hospital from that where the infant was born (OR: 3.7; CI: 2.20–6.22; p < 0.001) and the use of illicit drugs by the mother (OR: 3.2; CI: 1.57–6.87; p = 0.002). Only 33.7% (34/101) were followed until discharge. CONCLUSION: The majority of infants with reported congenital syphilis during this period did not attend the follow-up visits. Public health efforts aimed at reaching the parents of infants with CS should be a priority to ensure appropriate clinical identification and management of the associated outcomes of this vertically transmitted infection.
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spelling pubmed-102027252023-05-24 Follow-up of infants with congenital syphilis during the penicillin shortage period() Rocha, Ana Fátima Braga Araújo, Maria Alix Leite de Oliveira, Ana Karinne Dantas de Oliveira, Lucas Fernandes Pimentel, Lea Dias Gomes Vasconcelos Melo, Adriana Lopes Lima J Pediatr (Rio J) Original Article OBJECTIVE: To analyze the follow-up, in specialized outpatient clinics, of infants reported with congenital syphilis during the penicillin shortage. METHOD: A cross-sectional study was carried out in ten public maternity hospitals affiliated with the Brazilian Unified Health System in the city of Fortaleza, state of Ceará. Clinical records of infants reported with congenital syphilis who were born alive in 2015 were used to describe correlates of attendance at recommended clinical follow-up appointments. RESULTS: A total of 469 infants reported with CS from January 1/2015 to December 31/2015 were included in the analysis. The results show that most infants did not attend the follow-up visits (368/469, 78.5%) and the main associated factors are that the follow-up clinic is located in a different hospital from that where the infant was born (OR: 3.7; CI: 2.20–6.22; p < 0.001) and the use of illicit drugs by the mother (OR: 3.2; CI: 1.57–6.87; p = 0.002). Only 33.7% (34/101) were followed until discharge. CONCLUSION: The majority of infants with reported congenital syphilis during this period did not attend the follow-up visits. Public health efforts aimed at reaching the parents of infants with CS should be a priority to ensure appropriate clinical identification and management of the associated outcomes of this vertically transmitted infection. Elsevier 2022-12-27 /pmc/articles/PMC10202725/ /pubmed/36584977 http://dx.doi.org/10.1016/j.jped.2022.11.011 Text en © 2022 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Rocha, Ana Fátima Braga
Araújo, Maria Alix Leite
de Oliveira, Ana Karinne Dantas
de Oliveira, Lucas Fernandes
Pimentel, Lea Dias Gomes Vasconcelos
Melo, Adriana Lopes Lima
Follow-up of infants with congenital syphilis during the penicillin shortage period()
title Follow-up of infants with congenital syphilis during the penicillin shortage period()
title_full Follow-up of infants with congenital syphilis during the penicillin shortage period()
title_fullStr Follow-up of infants with congenital syphilis during the penicillin shortage period()
title_full_unstemmed Follow-up of infants with congenital syphilis during the penicillin shortage period()
title_short Follow-up of infants with congenital syphilis during the penicillin shortage period()
title_sort follow-up of infants with congenital syphilis during the penicillin shortage period()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202725/
https://www.ncbi.nlm.nih.gov/pubmed/36584977
http://dx.doi.org/10.1016/j.jped.2022.11.011
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