Dupilumab in patients with prurigo nodularis: two randomized, double-blind, placebo-controlled phase 3 trials

Prurigo nodularis (PN) is a chronic inflammatory skin disease with intensely pruritic nodules. The LIBERTY-PN PRIME and PRIME2 phase 3 trials enrolled adults with PN with ≥20 nodules and severe itch uncontrolled with topical therapies. Dupilumab, a fully human monoclonal antibody, blocks the shared...

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Detalles Bibliográficos
Autores principales: Yosipovitch, Gil, Mollanazar, Nicholas, Ständer, Sonja, Kwatra, Shawn G., Kim, Brian S., Laws, Elizabeth, Mannent, Leda P., Amin, Nikhil, Akinlade, Bolanle, Staudinger, Heribert W., Patel, Naimish, Yancopoulos, George D., Weinreich, David M., Wang, Sheldon, Shi, Genming, Bansal, Ashish, O’Malley, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202800/
https://www.ncbi.nlm.nih.gov/pubmed/37142763
http://dx.doi.org/10.1038/s41591-023-02320-9

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