Cingulin and paracingulin tether myosins-2 to junctions to mechanoregulate the plasma membrane

The mechanisms that regulate the spatial sorting of nonmuscle myosins-2 (NM2) isoforms and couple them mechanically to the plasma membrane are unclear. Here we show that the cytoplasmic junctional proteins cingulin (CGN) and paracingulin (CGNL1) interact directly with NM2s through their C-terminal c...

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Detalles Bibliográficos
Autores principales: Rouaud, Florian, Huang, Wenmao, Flinois, Arielle, Jain, Kunalika, Vasileva, Ekaterina, Di Mattia, Thomas, Mauperin, Marine, Parry, David A.D., Dugina, Vera, Chaponnier, Christine, Méan, Isabelle, Montessuit, Sylvie, Mutero-Maeda, Annick, Yan, Jie, Citi, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202830/
https://www.ncbi.nlm.nih.gov/pubmed/37204781
http://dx.doi.org/10.1083/jcb.202208065

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