Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy

Microscopy of mummified visceral tissue from a Medici family member in Italy identified a potential blood vessel containing erythrocytes. Giemsa staining, atomic force microscopy, and immunohistochemistry confirmed Plasmodium falciparum inside those erythrocytes. Our results indicate an ancient Medi...

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Detalles Bibliográficos
Autores principales: Maixner, Frank, Drescher, Dennis, Boccalini, Giulia, Piombino-Mascali, Dario, Janko, Marek, Berens-Riha, Nicole, Kim, Bum Jin, Gamble, Michelle, Schatterny, Jolanthe, Morty, Rory E., Ludwig, Melanie, Krause-Kyora, Ben, Stark, Robert, An, Hyun Joo, Neumann, Jens, Cipollini, Giovanna, Grimm, Rudolf, Kilian, Nicole, Zink, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202861/
https://www.ncbi.nlm.nih.gov/pubmed/37209696
http://dx.doi.org/10.3201/eid2906.230134
Descripción
Sumario:Microscopy of mummified visceral tissue from a Medici family member in Italy identified a potential blood vessel containing erythrocytes. Giemsa staining, atomic force microscopy, and immunohistochemistry confirmed Plasmodium falciparum inside those erythrocytes. Our results indicate an ancient Mediterranean presence of P. falciparum, which remains responsible for most malaria deaths in Africa.

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