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Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy

Microscopy of mummified visceral tissue from a Medici family member in Italy identified a potential blood vessel containing erythrocytes. Giemsa staining, atomic force microscopy, and immunohistochemistry confirmed Plasmodium falciparum inside those erythrocytes. Our results indicate an ancient Medi...

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Autores principales: Maixner, Frank, Drescher, Dennis, Boccalini, Giulia, Piombino-Mascali, Dario, Janko, Marek, Berens-Riha, Nicole, Kim, Bum Jin, Gamble, Michelle, Schatterny, Jolanthe, Morty, Rory E., Ludwig, Melanie, Krause-Kyora, Ben, Stark, Robert, An, Hyun Joo, Neumann, Jens, Cipollini, Giovanna, Grimm, Rudolf, Kilian, Nicole, Zink, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202861/
https://www.ncbi.nlm.nih.gov/pubmed/37209696
http://dx.doi.org/10.3201/eid2906.230134
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author Maixner, Frank
Drescher, Dennis
Boccalini, Giulia
Piombino-Mascali, Dario
Janko, Marek
Berens-Riha, Nicole
Kim, Bum Jin
Gamble, Michelle
Schatterny, Jolanthe
Morty, Rory E.
Ludwig, Melanie
Krause-Kyora, Ben
Stark, Robert
An, Hyun Joo
Neumann, Jens
Cipollini, Giovanna
Grimm, Rudolf
Kilian, Nicole
Zink, Albert
author_facet Maixner, Frank
Drescher, Dennis
Boccalini, Giulia
Piombino-Mascali, Dario
Janko, Marek
Berens-Riha, Nicole
Kim, Bum Jin
Gamble, Michelle
Schatterny, Jolanthe
Morty, Rory E.
Ludwig, Melanie
Krause-Kyora, Ben
Stark, Robert
An, Hyun Joo
Neumann, Jens
Cipollini, Giovanna
Grimm, Rudolf
Kilian, Nicole
Zink, Albert
author_sort Maixner, Frank
collection PubMed
description Microscopy of mummified visceral tissue from a Medici family member in Italy identified a potential blood vessel containing erythrocytes. Giemsa staining, atomic force microscopy, and immunohistochemistry confirmed Plasmodium falciparum inside those erythrocytes. Our results indicate an ancient Mediterranean presence of P. falciparum, which remains responsible for most malaria deaths in Africa.
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spelling pubmed-102028612023-06-01 Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy Maixner, Frank Drescher, Dennis Boccalini, Giulia Piombino-Mascali, Dario Janko, Marek Berens-Riha, Nicole Kim, Bum Jin Gamble, Michelle Schatterny, Jolanthe Morty, Rory E. Ludwig, Melanie Krause-Kyora, Ben Stark, Robert An, Hyun Joo Neumann, Jens Cipollini, Giovanna Grimm, Rudolf Kilian, Nicole Zink, Albert Emerg Infect Dis Research Letter Microscopy of mummified visceral tissue from a Medici family member in Italy identified a potential blood vessel containing erythrocytes. Giemsa staining, atomic force microscopy, and immunohistochemistry confirmed Plasmodium falciparum inside those erythrocytes. Our results indicate an ancient Mediterranean presence of P. falciparum, which remains responsible for most malaria deaths in Africa. Centers for Disease Control and Prevention 2023-06 /pmc/articles/PMC10202861/ /pubmed/37209696 http://dx.doi.org/10.3201/eid2906.230134 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Maixner, Frank
Drescher, Dennis
Boccalini, Giulia
Piombino-Mascali, Dario
Janko, Marek
Berens-Riha, Nicole
Kim, Bum Jin
Gamble, Michelle
Schatterny, Jolanthe
Morty, Rory E.
Ludwig, Melanie
Krause-Kyora, Ben
Stark, Robert
An, Hyun Joo
Neumann, Jens
Cipollini, Giovanna
Grimm, Rudolf
Kilian, Nicole
Zink, Albert
Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy
title Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy
title_full Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy
title_fullStr Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy
title_full_unstemmed Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy
title_short Microscopic Evidence of Malaria Infection in Visceral Tissue from Medici Family, Italy
title_sort microscopic evidence of malaria infection in visceral tissue from medici family, italy
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202861/
https://www.ncbi.nlm.nih.gov/pubmed/37209696
http://dx.doi.org/10.3201/eid2906.230134
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