Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung

Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed limited replication efficiency in bronchial and lung tissue but had a higher replication than avian H3N8 vir...

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Detalles Bibliográficos
Autores principales: Hui, Kenrie P.Y., Ho, John C.W., Ng, Ka-Chun, Cheng, Samuel M.S., Sit, Ko-Yung, Au, Timmy W.K., Poon, Leo L.M., Nicholls, John M., Peiris, Malik, Chan, Michael C.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202868/
https://www.ncbi.nlm.nih.gov/pubmed/37095078
http://dx.doi.org/10.3201/eid2906.221680
Descripción
Sumario:Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed limited replication efficiency in bronchial and lung tissue but had a higher replication than avian H3N8 virus in lung tissue.

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