Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung

Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed limited replication efficiency in bronchial and lung tissue but had a higher replication than avian H3N8 vir...

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Autores principales: Hui, Kenrie P.Y., Ho, John C.W., Ng, Ka-Chun, Cheng, Samuel M.S., Sit, Ko-Yung, Au, Timmy W.K., Poon, Leo L.M., Nicholls, John M., Peiris, Malik, Chan, Michael C.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202868/
https://www.ncbi.nlm.nih.gov/pubmed/37095078
http://dx.doi.org/10.3201/eid2906.221680
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author Hui, Kenrie P.Y.
Ho, John C.W.
Ng, Ka-Chun
Cheng, Samuel M.S.
Sit, Ko-Yung
Au, Timmy W.K.
Poon, Leo L.M.
Nicholls, John M.
Peiris, Malik
Chan, Michael C.W.
author_facet Hui, Kenrie P.Y.
Ho, John C.W.
Ng, Ka-Chun
Cheng, Samuel M.S.
Sit, Ko-Yung
Au, Timmy W.K.
Poon, Leo L.M.
Nicholls, John M.
Peiris, Malik
Chan, Michael C.W.
author_sort Hui, Kenrie P.Y.
collection PubMed
description Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed limited replication efficiency in bronchial and lung tissue but had a higher replication than avian H3N8 virus in lung tissue.
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spelling pubmed-102028682023-06-01 Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung Hui, Kenrie P.Y. Ho, John C.W. Ng, Ka-Chun Cheng, Samuel M.S. Sit, Ko-Yung Au, Timmy W.K. Poon, Leo L.M. Nicholls, John M. Peiris, Malik Chan, Michael C.W. Emerg Infect Dis Dispatch Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed limited replication efficiency in bronchial and lung tissue but had a higher replication than avian H3N8 virus in lung tissue. Centers for Disease Control and Prevention 2023-06 /pmc/articles/PMC10202868/ /pubmed/37095078 http://dx.doi.org/10.3201/eid2906.221680 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Hui, Kenrie P.Y.
Ho, John C.W.
Ng, Ka-Chun
Cheng, Samuel M.S.
Sit, Ko-Yung
Au, Timmy W.K.
Poon, Leo L.M.
Nicholls, John M.
Peiris, Malik
Chan, Michael C.W.
Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung
title Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung
title_full Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung
title_fullStr Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung
title_full_unstemmed Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung
title_short Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung
title_sort replication of novel zoonotic-like influenza a(h3n8) virus in ex vivo human bronchus and lung
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202868/
https://www.ncbi.nlm.nih.gov/pubmed/37095078
http://dx.doi.org/10.3201/eid2906.221680
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