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Isolated Ocular Mpox without Skin Lesions, United States

We report a case of a 53-year-old HIV-negative patient in San Francisco, California, USA, with no classic mpox prodromal symptoms or skin lesions who experienced fulminant, vision-threatening scleritis, keratitis, and uveitis. Deep sequence analysis identified monkeypox virus RNA in the aqueous humo...

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Autores principales: Nguyen, Minh T., Mentreddy, Akshay, Schallhorn, Julie, Chan, Matilda, Aung, Su, Doernberg, Sarah B., Babik, Jennifer, Miles, Kevin, Yang, Katherine, Lydon, Emily, Minter, Daniel J., Gonzales, John, Shantha, Jessica, Doan, Thuy, Seitzman, Gerami D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202873/
https://www.ncbi.nlm.nih.gov/pubmed/37130504
http://dx.doi.org/10.3201/eid2906.230032
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author Nguyen, Minh T.
Mentreddy, Akshay
Schallhorn, Julie
Chan, Matilda
Aung, Su
Doernberg, Sarah B.
Babik, Jennifer
Miles, Kevin
Yang, Katherine
Lydon, Emily
Minter, Daniel J.
Gonzales, John
Shantha, Jessica
Doan, Thuy
Seitzman, Gerami D.
author_facet Nguyen, Minh T.
Mentreddy, Akshay
Schallhorn, Julie
Chan, Matilda
Aung, Su
Doernberg, Sarah B.
Babik, Jennifer
Miles, Kevin
Yang, Katherine
Lydon, Emily
Minter, Daniel J.
Gonzales, John
Shantha, Jessica
Doan, Thuy
Seitzman, Gerami D.
author_sort Nguyen, Minh T.
collection PubMed
description We report a case of a 53-year-old HIV-negative patient in San Francisco, California, USA, with no classic mpox prodromal symptoms or skin lesions who experienced fulminant, vision-threatening scleritis, keratitis, and uveitis. Deep sequence analysis identified monkeypox virus RNA in the aqueous humor. We confirmed the virus on the cornea and sclera by PCR.
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spelling pubmed-102028732023-06-01 Isolated Ocular Mpox without Skin Lesions, United States Nguyen, Minh T. Mentreddy, Akshay Schallhorn, Julie Chan, Matilda Aung, Su Doernberg, Sarah B. Babik, Jennifer Miles, Kevin Yang, Katherine Lydon, Emily Minter, Daniel J. Gonzales, John Shantha, Jessica Doan, Thuy Seitzman, Gerami D. Emerg Infect Dis Research Letter We report a case of a 53-year-old HIV-negative patient in San Francisco, California, USA, with no classic mpox prodromal symptoms or skin lesions who experienced fulminant, vision-threatening scleritis, keratitis, and uveitis. Deep sequence analysis identified monkeypox virus RNA in the aqueous humor. We confirmed the virus on the cornea and sclera by PCR. Centers for Disease Control and Prevention 2023-06 /pmc/articles/PMC10202873/ /pubmed/37130504 http://dx.doi.org/10.3201/eid2906.230032 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Nguyen, Minh T.
Mentreddy, Akshay
Schallhorn, Julie
Chan, Matilda
Aung, Su
Doernberg, Sarah B.
Babik, Jennifer
Miles, Kevin
Yang, Katherine
Lydon, Emily
Minter, Daniel J.
Gonzales, John
Shantha, Jessica
Doan, Thuy
Seitzman, Gerami D.
Isolated Ocular Mpox without Skin Lesions, United States
title Isolated Ocular Mpox without Skin Lesions, United States
title_full Isolated Ocular Mpox without Skin Lesions, United States
title_fullStr Isolated Ocular Mpox without Skin Lesions, United States
title_full_unstemmed Isolated Ocular Mpox without Skin Lesions, United States
title_short Isolated Ocular Mpox without Skin Lesions, United States
title_sort isolated ocular mpox without skin lesions, united states
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202873/
https://www.ncbi.nlm.nih.gov/pubmed/37130504
http://dx.doi.org/10.3201/eid2906.230032
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