Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China

We report a case of murine typhus in China caused by Rickettsia typhi and diagnosed by nanopore targeted sequencing of a bronchoalveolar lavage fluid sample. This case highlights that nanopore targeted sequencing can effectively detect clinically unexplained infections and be especially useful for d...

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Detalles Bibliográficos
Autores principales: Qian, Panpan, He, Xiaohua, Yang, Mei, Wei, Li, Zhang, Lihui, Xing, Xiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202882/
https://www.ncbi.nlm.nih.gov/pubmed/37209688
http://dx.doi.org/10.3201/eid2906.221929
Descripción
Sumario:We report a case of murine typhus in China caused by Rickettsia typhi and diagnosed by nanopore targeted sequencing of a bronchoalveolar lavage fluid sample. This case highlights that nanopore targeted sequencing can effectively detect clinically unexplained infections and be especially useful for detecting infections in patients without typical signs and symptoms.

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