Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China

We report a case of murine typhus in China caused by Rickettsia typhi and diagnosed by nanopore targeted sequencing of a bronchoalveolar lavage fluid sample. This case highlights that nanopore targeted sequencing can effectively detect clinically unexplained infections and be especially useful for d...

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Detalles Bibliográficos
Autores principales: Qian, Panpan, He, Xiaohua, Yang, Mei, Wei, Li, Zhang, Lihui, Xing, Xiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202882/
https://www.ncbi.nlm.nih.gov/pubmed/37209688
http://dx.doi.org/10.3201/eid2906.221929
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author Qian, Panpan
He, Xiaohua
Yang, Mei
Wei, Li
Zhang, Lihui
Xing, Xiqian
author_facet Qian, Panpan
He, Xiaohua
Yang, Mei
Wei, Li
Zhang, Lihui
Xing, Xiqian
author_sort Qian, Panpan
collection PubMed
description We report a case of murine typhus in China caused by Rickettsia typhi and diagnosed by nanopore targeted sequencing of a bronchoalveolar lavage fluid sample. This case highlights that nanopore targeted sequencing can effectively detect clinically unexplained infections and be especially useful for detecting infections in patients without typical signs and symptoms.
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spelling pubmed-102028822023-06-01 Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China Qian, Panpan He, Xiaohua Yang, Mei Wei, Li Zhang, Lihui Xing, Xiqian Emerg Infect Dis Research Letter We report a case of murine typhus in China caused by Rickettsia typhi and diagnosed by nanopore targeted sequencing of a bronchoalveolar lavage fluid sample. This case highlights that nanopore targeted sequencing can effectively detect clinically unexplained infections and be especially useful for detecting infections in patients without typical signs and symptoms. Centers for Disease Control and Prevention 2023-06 /pmc/articles/PMC10202882/ /pubmed/37209688 http://dx.doi.org/10.3201/eid2906.221929 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Qian, Panpan
He, Xiaohua
Yang, Mei
Wei, Li
Zhang, Lihui
Xing, Xiqian
Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China
title Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China
title_full Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China
title_fullStr Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China
title_full_unstemmed Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China
title_short Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China
title_sort detection of severe murine typhus by nanopore targeted sequencing, china
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202882/
https://www.ncbi.nlm.nih.gov/pubmed/37209688
http://dx.doi.org/10.3201/eid2906.221929
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