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Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT

Photon-counting detector (PCD) CT allows for ultra-high-resolution (UHR) examinations of the shoulder without requiring an additional post-patient comb filter to narrow the detector aperture. This study was designed to compare the PCD performance with a high-end energy-integrating detector (EID) CT....

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Autores principales: Patzer, Theresa Sophie, Kunz, Andreas Steven, Huflage, Henner, Luetkens, Karsten Sebastian, Conrads, Nora, Gruschwitz, Philipp, Pannenbecker, Pauline, Ergün, Süleyman, Bley, Thorsten Alexander, Grunz, Jan-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202924/
https://www.ncbi.nlm.nih.gov/pubmed/37217553
http://dx.doi.org/10.1038/s41598-023-35367-2
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author Patzer, Theresa Sophie
Kunz, Andreas Steven
Huflage, Henner
Luetkens, Karsten Sebastian
Conrads, Nora
Gruschwitz, Philipp
Pannenbecker, Pauline
Ergün, Süleyman
Bley, Thorsten Alexander
Grunz, Jan-Peter
author_facet Patzer, Theresa Sophie
Kunz, Andreas Steven
Huflage, Henner
Luetkens, Karsten Sebastian
Conrads, Nora
Gruschwitz, Philipp
Pannenbecker, Pauline
Ergün, Süleyman
Bley, Thorsten Alexander
Grunz, Jan-Peter
author_sort Patzer, Theresa Sophie
collection PubMed
description Photon-counting detector (PCD) CT allows for ultra-high-resolution (UHR) examinations of the shoulder without requiring an additional post-patient comb filter to narrow the detector aperture. This study was designed to compare the PCD performance with a high-end energy-integrating detector (EID) CT. Sixteen cadaveric shoulders were examined with both scanners using dose-matched 120 kVp acquisition protocols (low-dose/full-dose: CTDI(vol) = 5.0/10.0 mGy). Specimens were scanned in UHR mode with the PCD-CT, whereas EID-CT examinations were conducted in accordance with the clinical standard as “non-UHR”. Reconstruction of EID data employed the sharpest kernel available for standard-resolution scans (ρ(50) = 12.3 lp/cm), while PCD data were reconstructed with both a comparable kernel (11.8 lp/cm) and a sharper dedicated bone kernel (16.5 lp/cm). Six radiologists with 2–9 years of experience in musculoskeletal imaging rated image quality subjectively. Interrater agreement was analyzed by calculation of the intraclass correlation coefficient in a two-way random effects model. Quantitative analyses comprised noise recording and calculating signal-to-noise ratios based on attenuation measurements in bone and soft tissue. Subjective image quality was higher in UHR-PCD-CT than in EID-CT and non-UHR-PCD-CT datasets (all p < 0.001). While low-dose UHR-PCD-CT was considered superior to full-dose non-UHR studies on either scanner (all p < 0.001), ratings of low-dose non-UHR-PCD-CT and full-dose EID-CT examinations did not differ (p > 0.99). Interrater reliability was moderate, indicated by a single measures intraclass correlation coefficient of 0.66 (95% confidence interval: 0.58–0.73; p < 0.001). Image noise was lowest and signal-to-noise ratios were highest in non-UHR-PCD-CT reconstructions at either dose level (p < 0.001). This investigation demonstrates that superior depiction of trabecular microstructure and considerable denoising can be realized without additional radiation dose by employing a PCD for shoulder CT imaging. Allowing for UHR scans without dose penalty, PCD-CT appears as a promising alternative to EID-CT for shoulder trauma assessment in clinical routine.
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spelling pubmed-102029242023-05-24 Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT Patzer, Theresa Sophie Kunz, Andreas Steven Huflage, Henner Luetkens, Karsten Sebastian Conrads, Nora Gruschwitz, Philipp Pannenbecker, Pauline Ergün, Süleyman Bley, Thorsten Alexander Grunz, Jan-Peter Sci Rep Article Photon-counting detector (PCD) CT allows for ultra-high-resolution (UHR) examinations of the shoulder without requiring an additional post-patient comb filter to narrow the detector aperture. This study was designed to compare the PCD performance with a high-end energy-integrating detector (EID) CT. Sixteen cadaveric shoulders were examined with both scanners using dose-matched 120 kVp acquisition protocols (low-dose/full-dose: CTDI(vol) = 5.0/10.0 mGy). Specimens were scanned in UHR mode with the PCD-CT, whereas EID-CT examinations were conducted in accordance with the clinical standard as “non-UHR”. Reconstruction of EID data employed the sharpest kernel available for standard-resolution scans (ρ(50) = 12.3 lp/cm), while PCD data were reconstructed with both a comparable kernel (11.8 lp/cm) and a sharper dedicated bone kernel (16.5 lp/cm). Six radiologists with 2–9 years of experience in musculoskeletal imaging rated image quality subjectively. Interrater agreement was analyzed by calculation of the intraclass correlation coefficient in a two-way random effects model. Quantitative analyses comprised noise recording and calculating signal-to-noise ratios based on attenuation measurements in bone and soft tissue. Subjective image quality was higher in UHR-PCD-CT than in EID-CT and non-UHR-PCD-CT datasets (all p < 0.001). While low-dose UHR-PCD-CT was considered superior to full-dose non-UHR studies on either scanner (all p < 0.001), ratings of low-dose non-UHR-PCD-CT and full-dose EID-CT examinations did not differ (p > 0.99). Interrater reliability was moderate, indicated by a single measures intraclass correlation coefficient of 0.66 (95% confidence interval: 0.58–0.73; p < 0.001). Image noise was lowest and signal-to-noise ratios were highest in non-UHR-PCD-CT reconstructions at either dose level (p < 0.001). This investigation demonstrates that superior depiction of trabecular microstructure and considerable denoising can be realized without additional radiation dose by employing a PCD for shoulder CT imaging. Allowing for UHR scans without dose penalty, PCD-CT appears as a promising alternative to EID-CT for shoulder trauma assessment in clinical routine. Nature Publishing Group UK 2023-05-22 /pmc/articles/PMC10202924/ /pubmed/37217553 http://dx.doi.org/10.1038/s41598-023-35367-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Patzer, Theresa Sophie
Kunz, Andreas Steven
Huflage, Henner
Luetkens, Karsten Sebastian
Conrads, Nora
Gruschwitz, Philipp
Pannenbecker, Pauline
Ergün, Süleyman
Bley, Thorsten Alexander
Grunz, Jan-Peter
Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT
title Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT
title_full Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT
title_fullStr Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT
title_full_unstemmed Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT
title_short Quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector CT
title_sort quantitative and qualitative image quality assessment in shoulder examinations with a first-generation photon-counting detector ct
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202924/
https://www.ncbi.nlm.nih.gov/pubmed/37217553
http://dx.doi.org/10.1038/s41598-023-35367-2
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