Alkali-labile gangliosides

The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac(2), and of gangliosides carrying a sialic acid that...

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Detalles Bibliográficos
Autores principales: Mauri, Laura, Sonnino, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Comprehensive Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202986/
https://www.ncbi.nlm.nih.gov/pubmed/36695939
http://dx.doi.org/10.1007/s10719-023-10103-0
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author Mauri, Laura
Sonnino, Sandro
author_facet Mauri, Laura
Sonnino, Sandro
author_sort Mauri, Laura
collection PubMed
description The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac(2), and of gangliosides carrying a sialic acid that forms a lactone ring. Starting from biochemical data we will discuss the possible biochemical role played by these gangliosides in the processes of cell signaling and maintenance of brain functions.
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spelling pubmed-102029862023-05-24 Alkali-labile gangliosides Mauri, Laura Sonnino, Sandro Glycoconj J Comprehensive Review Article The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac(2), and of gangliosides carrying a sialic acid that forms a lactone ring. Starting from biochemical data we will discuss the possible biochemical role played by these gangliosides in the processes of cell signaling and maintenance of brain functions. Springer US 2023-01-25 2023 /pmc/articles/PMC10202986/ /pubmed/36695939 http://dx.doi.org/10.1007/s10719-023-10103-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comprehensive Review Article
Mauri, Laura
Sonnino, Sandro
Alkali-labile gangliosides
title Alkali-labile gangliosides
title_full Alkali-labile gangliosides
title_fullStr Alkali-labile gangliosides
title_full_unstemmed Alkali-labile gangliosides
title_short Alkali-labile gangliosides
title_sort alkali-labile gangliosides
topic Comprehensive Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202986/
https://www.ncbi.nlm.nih.gov/pubmed/36695939
http://dx.doi.org/10.1007/s10719-023-10103-0
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