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Human variation impacting MCOLN2 restricts Salmonella Typhi replication by magnesium deprivation

Human genetic diversity can reveal critical factors in host-pathogen interactions. This is especially useful for human-restricted pathogens like Salmonella enterica serovar Typhi (S. Typhi), the cause of typhoid fever. One key defense during bacterial infection is nutritional immunity: host cells at...

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Detalles Bibliográficos
Autores principales: Gibbs, Kyle D., Wang, Liuyang, Yang, Zhuo, Anderson, Caroline E., Bourgeois, Jeffrey S., Cao, Yanlu, Gaggioli, Margaret R., Biel, Martin, Puertollano, Rosa, Chen, Cheng-Chang, Ko, Dennis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203047/
https://www.ncbi.nlm.nih.gov/pubmed/37228749
http://dx.doi.org/10.1016/j.xgen.2023.100290