Novel genetically engineered mouse models for clear cell renal cell carcinoma

Genetically engineered mouse models (GEMMs) are important immunocompetent models for research into the roles of individual genes in cancer and the development of novel therapies. Here we use inducible CRISPR-Cas9 systems to develop two GEMMs which aim to model the extensive chromosome p3 deletion fr...

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Detalles Bibliográficos
Autores principales: van der Mijn, Johannes C., Laursen, Kristian B., Fu, Leiping, Khani, Francesca, Dow, Lukas E., Nowak, Dawid G., Chen, Qiuying, Gross, Steven S., Nanus, David M., Gudas, Lorraine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203127/
https://www.ncbi.nlm.nih.gov/pubmed/37217526
http://dx.doi.org/10.1038/s41598-023-35106-7

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