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A method for restoring signals and revealing individual macromolecule states in cryo-ET, REST

Cryo-electron tomography (cryo-ET) is widely used to explore the 3D density of biomacromolecules. However, the heavy noise and missing wedge effect prevent directly visualizing and analyzing the 3D reconstructions. Here, we introduced REST, a deep learning strategy-based method to establish the rela...

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Detalles Bibliográficos
Autores principales: Zhang, Haonan, Li, Yan, Liu, Yanan, Li, Dongyu, Wang, Lin, Song, Kai, Bao, Keyan, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203133/
https://www.ncbi.nlm.nih.gov/pubmed/37217501
http://dx.doi.org/10.1038/s41467-023-38539-w

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