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A method for restoring signals and revealing individual macromolecule states in cryo-ET, REST
Cryo-electron tomography (cryo-ET) is widely used to explore the 3D density of biomacromolecules. However, the heavy noise and missing wedge effect prevent directly visualizing and analyzing the 3D reconstructions. Here, we introduced REST, a deep learning strategy-based method to establish the rela...
Autores principales: | Zhang, Haonan, Li, Yan, Liu, Yanan, Li, Dongyu, Wang, Lin, Song, Kai, Bao, Keyan, Zhu, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203133/ https://www.ncbi.nlm.nih.gov/pubmed/37217501 http://dx.doi.org/10.1038/s41467-023-38539-w |
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