Mass Cytometry reveals unique phenotypic patterns associated with subclonal diversity and outcomes in multiple myeloma

Multiple myeloma (MM) remains an incurable plasma cell (PC) malignancy. Although it is known that MM tumor cells display extensive intratumoral genetic heterogeneity, an integrated map of the tumor proteomic landscape has not been comprehensively evaluated. We evaluated 49 primary tumor samples from...

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Detalles Bibliográficos
Autores principales: Baughn, Linda B., Jessen, Erik, Sharma, Neeraj, Tang, Hongwei, Smadbeck, James B., Long, Mark D., Pearce, Kathryn, Smith, Matthew, Dasari, Surendra, Sachs, Zohar, Linden, Michael A., Cook, Joselle, Keith Stewart, A., Chesi, Marta, Mitra, Amit, Leif Bergsagel, P., Van Ness, Brian, Kumar, Shaji K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203138/
https://www.ncbi.nlm.nih.gov/pubmed/37217482
http://dx.doi.org/10.1038/s41408-023-00851-5

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