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Duchenne muscular dystrophy disease severity impacts skeletal muscle progenitor cells systemic delivery

Duchenne muscular dystrophy (DMD) is caused by an out-of-frame mutation in the DMD gene that results in the absence of a functional dystrophin protein, leading to a devastating progressive lethal muscle-wasting disease. Muscle stem cell-based therapy is a promising avenue for improving muscle regene...

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Detalles Bibliográficos
Autores principales: Saleh, Kholoud K., Switzler, Corey, Hicks, Michael R., Gane, Lily, Gibbs, Devin E., Pyle, April D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203213/
https://www.ncbi.nlm.nih.gov/pubmed/37228827
http://dx.doi.org/10.3389/fphys.2023.1190524