Cargando…

GADD34 activates p53 and may have utility as a marker of atherosclerosis

We previously identified growth arrest and DNA-damage-inducible gene 34 (GADD34) as a marker of ischemic stroke. In the present study, serum levels of anti-GADD34 antibodies were found to be significantly higher in patients with acute ischemic stroke or chronic kidney disease compared to healthy don...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tomiyoshi, Go, Nakamura, Rika, Shinmen, Natsuko, Yoshida, Yoichi, Mine, Seiichiro, Machida, Toshio, Iwase, Katsuro, Iwadate, Yasuo, Hiwasa, Takaki, Kuroda, Hideyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203227/ https://www.ncbi.nlm.nih.gov/pubmed/37228401 http://dx.doi.org/10.3389/fmed.2023.1128921

Ejemplares similares

Serum anti-AP3D1 antibodies are risk factors for acute ischemic stroke related with atherosclerosis
por: Li, Shu-Yang, et al.
Publicado: (2021)

Elevated levels of autoantibodies against DNAJC2 in sera of patients with atherosclerotic diseases
por: Yoshida, Yoichi, et al.
Publicado: (2020)

Association between serum anti-ASXL2 antibody levels and acute ischemic stroke, acute myocardial infarction, diabetes mellitus, chronic kidney disease and digestive organ cancer, and their possible association with atherosclerosis and hypertension
por: Li, Shu-Yang, et al.
Publicado: (2020)

Circulating Anti-Sorting Nexins 16 Antibodies as an Emerging Biomarker of Coronary Artery Disease in Patients with Obstructive Sleep Apnea
por: Katsumata, Yusuke, et al.
Publicado: (2020)

Elevation of Autoantibody in Patients with Ischemic Stroke
por: YOSHIDA, Yoichi, et al.
Publicado: (2018)

Elevation of autoantibody level against PDCD11 in patients with transient ischemic attack
por: Yoshida, Yoichi, et al.
Publicado: (2017)

Serum anti‑TSTD2 antibody as a biomarker for atherosclerosis‑induced ischemic stroke and chronic kidney disease
por: Kubota, Masaaki, et al.
Publicado: (2022)

Association of serum levels of antibodies against ALDOA and FH4 with transient ischemic attack and cerebral infarction
por: Wang, Hao, et al.
Publicado: (2021)

Elevated Adiponectin Antibody Levels in Sera of Patients with Atherosclerosis-Related Coronary Artery Disease, Cerebral Infarction and Diabetes Mellitus
por: Hiwasa, Takaki, et al.
Publicado: (2016)

Serum anti-SERPINE1 antibody as a potential biomarker of acute cerebral infarction
por: Kubota, Masaaki, et al.
Publicado: (2021)

Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction
por: Wang, Hao, et al.
Publicado: (2017)

Utility of atherosclerosis-associated serum antibodies against colony-stimulating factor 2 in predicting the onset of acute ischemic stroke and prognosis of colorectal cancer
por: Li, Shu-Yang, et al.
Publicado: (2023)

Serum anti-PCK1 antibody levels are a prognostic factor for patients with diabetes mellitus
por: Namiki, Toshiki, et al.
Publicado: (2023)

Identification of stroke-associated-antigens via screening of recombinant proteins from the human expression cDNA library (SEREX)
por: Machida, Toshio, et al.
Publicado: (2015)

Serum anti‐LRPAP1 is a common biomarker for digestive organ cancers and atherosclerotic diseases
por: Sumazaki, Makoto, et al.
Publicado: (2020)

Role of Evaluating MGMT Status and 1p36 Deletion in Radiosurgery-Induced Anaplastic Ependymoma That Rapidly and Completely Resolved by Temozolomide Alone: Case Report and Review of the Literature
por: Hirono, Seiichiro, et al.
Publicado: (2015)

Real-time methylation-specific PCR for the evaluation of methylation status of MGMT gene in glioblastoma
por: Yoshioka, Masaki, et al.
Publicado: (2018)

GADD34 is a modulator of autophagy during starvation
por: Gambardella, Gennaro, et al.
Publicado: (2020)

Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke
por: Hiwasa, Takaki, et al.
Publicado: (2021)

Autologous antibody to src-homology 3-domain GRB2-like 1 specifically increases in the sera of patients with low-grade gliomas
por: Matsutani, Tomoo, et al.
Publicado: (2012)

Negative Regulation of GADD34 on Myofibroblasts during Cutaneous Wound Healing
por: Liu, Lintao, et al.
Publicado: (2014)

EBNA3C interacts with Gadd34 and counteracts the unfolded protein response
por: Garrido, Jose L, et al.
Publicado: (2009)

GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
por: Ito, Sachiko, et al.
Publicado: (2015)

Circulating anti-filamin C autoantibody as a potential serum biomarker for low-grade gliomas
por: Adachi-Hayama, Masayo, et al.
Publicado: (2014)

Enhancement of the Acrolein-Induced Production of Reactive Oxygen Species and Lung Injury by GADD34
por: Sun, Yang, et al.
Publicado: (2015)

GADD34 Ablation Exacerbates Retinal Degeneration in P23H RHO Mice
por: Saltykova, Irina V., et al.
Publicado: (2022)

Effects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice
por: Tanaka, Yuriko, et al.
Publicado: (2015)

Gadd45β and Gadd45γ are critical for regulating autoimmunity
por: Liu, Lin, et al.
Publicado: (2005)

Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels
por: Arasawa, Takahiro, et al.
Publicado: (2023)

Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α
por: Novoa, Isabel, et al.
Publicado: (2001)

HTLV-1 HBZ activates mTOR signaling pathway via inhibition of GADD34
por: Mukai, Risa, et al.
Publicado: (2011)

GADD34 induces cell death through inactivation of Akt following traumatic brain injury
por: Farook, J M, et al.
Publicado: (2013)

GADD34 induces cell death through inactivation of Akt following traumatic brain injury
por: Farook, J M, et al.
Publicado: (2013)

GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation
por: Ito, S, et al.
Publicado: (2016)

GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy
por: Holczer, Marianna, et al.
Publicado: (2016)

Molecular docking studies of salubrinal and its analogs as inhibitors of the GADD34:PP1 enzyme
por: Zadorozhnii, Pavlo V., et al.
Publicado: (2019)

MPC-8 Serum anti-zinc finger FYVE domain-containing protein 21 (ZFYVE21) autoantibody as a novel biomarker for oligodendroglioma IDH-mutant and 1p/19q co-deletion
por: Matsutani, Tomoo, et al.
Publicado: (2021)

Geoffrey Michael Gadd
por: Gadd, Geoffrey Michael
Publicado: (2020)

NQPC-05 BEVACIZUMAB AFTER PROGRESSION OF GLIOBLASTOMA PROLONGS PATIENT’S LIVING TIME AT HOME IN THE LAST 90 DAYS
por: Matsutani, Tomoo, et al.
Publicado: (2019)

STMO-05 SURGICAL AND FUNCTIONAL OUTCOME OF AWAKE SURGERY FOR INSULAR GLIOMA
por: Hirono, Seiichiro, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_h86tjuaj6odf26oo468dlqhdu1